טייסברי - Tysabri – ויקיתרופות

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01/03/2008

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1. ××ª×¨××¤× ×××××¨× ×ª×× ×ª× ×××× ××ª×¨×¤×× ××××¤×× ××¦××¨××ª ××ª×§×¤×××ª (relapsing) ×©× ××¨×©×ª × ×¤××¦× ××××ª×§××× ××× ××××: ×. ××§× ×©× × ××××× ××××¨ ××©××× ××××¤×× ×§××× ×××©× ×©× × ××¤×××ª ×××××× ××¢×× ×× ×¢× ××× ××××: 1. ××× ××ª×§×£ ××× ××¤×××ª ××××× ××©× × ××××¨×× × ×ª××ª ××××¤×× ××§××× ××××××§×ª MRI × ×¦×¤× 9 × ××¢×× ×-T2 ×× ××¤×××ª × ××¢ ××× ××¢×××¨ ××××¨× ××××××× ×××. 2. ××××× ××©×¨ ×©××¢××¨ ×××ª×§×¤×× ××©× × ×©××× ×× ×××× ×××ª×¨ ××¢×ª ××××¤×× ××ª××©××¨ ××××¡ ××©× × ×©×§××× ××ª××××ª ××××¤××. ×. ××§× ×¨××©×× ×××××× ×¢× ×××× ×¡××¢×¨×ª ×××××¤××× ×ª ×-2 ××ª×§×¤×× ×× ×××ª×¨ ××©× × ×××ª, ×××¤×××ª × ××¢ ××× ××¢×××¨ ××××¨× ××××××× ××× ×× ×¢××× ×× ××¢×× ×-T2 ××××¦×× MRI ××××¡ ××××¦×× MRI ×§×××××. ×. ×××××× ××©×¨ ×¤××ª×× ×ª××¤×¢××ª ××××× ×§×©××ª ××ª××¦×× ××××¤×× ×§××× ×× ×- Interferon beta ××× ×-Glatiramer acetate ××©×¨ ×××¢×ª ××¨××¤× ××××¤× ×× ×××¤×©×¨××ª ××ª ×××©× ××××¤××. 2. ××××¤×× ××ª×¨××¤× ××¢×©× ×¢× ×¤× ××¨×©× ×©× ×¨××¤× ××××× ×× ×××¨××××××.	01/03/2008	× ×××¨××××××	××¨×©×ª × ×¤××¦×, Multiple sclerosis
×. ××ª×¨××¤× ×ª×× ×ª× ××××¤×× ×××××× ×¢× ×××× × ××××××ª ×©× ××¨×©×ª × ×¤××¦× (×¢× ×¤× ××§×¨×××¨××× ×× ××¢××× ××× ×¢× ×©× McDonald) ×¢× ×××× ×¤×¢××× ×× Clinically Isolated Syndrome (CIS), ×××ª×× ××ª× ×× ××¨××©××. ××××¤×× ×× ××× ×ª× ×××××× ×¢× ×××× ×¤×¨×××¨×¡××××ª ×¨××©×× ××ª (PPMS) ×× ×¤×¨×××¨×¡××××ª ×©× ××× ××ª ×¤×¢××× (SPMS) ×©××× × ××××¤××× ××ª×¨××¤××ª ×××¢×××××ª ×××¨×©×ª × ×¤××¦×. ×. ××××¤×× ××× ×ª× ×××× ××ª×¨×¤××. ×. ××ª×××ª ××××¤×× ××ª×¨××¤× ×ª××¢×©× ××¤× ××¨×©× ×©× × ×××¨× ××××× ×××× ×©×¢××¨ ××©×ª××××ª ×¢×××ª××, ×× × ×××¨×××× ××××× ×©×¢××¨ ××©×ª××××ª ×¢×××ª×× ×××¨×©×ª × ×¤××¦×, ×× ××××× ×× ×××¨×××××× ××¢××× ×××¨×¤××ª ××¨×©×ª × ×¤××¦× ×× ××¨×¤×× × ×××¨×××××× ××××××ª ×××¢××××ª.	03/02/2022	× ×××¨××××××	××¨×©×ª × ×¤××¦×, Multiple sclerosis
×. ××ª×¨××¤× ×ª×× ×ª× ××××¤×× ×××§×¨×× ××××: 1. ×××× ××ª×¨×¤×× ×××××× ×¢× ×××× × ××××××ª ×©× ××¨×©×ª × ×¤××¦× (×¢× ×¤× ××§×¨×××¨××× ×× ××¢××× ××× ×¢× ×©× McDonald) ×¢× ×××× ×¤×¢××× ×××× ×××× ×¤×¨×××¨×¡××××ª ×©× ××× ××ª ×¤×¢××× (active SPMS) ×× Clinically Isolated Syndrome (CIS), ×××ª×× ××ª× ×× ××¨××©××. ××××¤×× ×× ××× ×ª× ×××××× ×¢× ×××× ×¤×¨×××¨×¡××××ª ×¨××©×× ××ª (PPMS) ×©××× × ××××¤××× ××ª×¨××¤××ª ×××¢×××××ª ×××¨×©×ª × ×¤××¦×. 2. ×××× ××ª×¨×¤××, ×××××× ×¢× ×××× × ××××××ª ×©× ××¨×©×ª × ×¤××¦× ××××× ×¤×¨×××¨×¡××× ×©× ××× × (SPMS) ×¢× ×××¡×××¨×× ×©× RRMS, ×©×× ×¢× EDSS ××¢×¨× 7.5 ×××× ××¢×××ª ××××× ×¤×¢××× (××¢× ××× ×× ×××× ×¤×¢××× ×ª××××¨ ×××× ×××× - ××××¨× ××©× × ××××¨×× ×, ×¤×¢××××ª ×××©× ××××××¨×ª ××¤× × ××¢×× ×××©××, ××¨××× ×©× × ××¢×× ×§××××× ×× × ××¢×× ×§××××× ××××¨× × ×××× ××©× × ××××¨×× × ×××××××ª MRI), ×××××¨× ×§××× ××ª ××ª××¢××ª ×× ××ª×§××××ª ×¨×¦××¤× ×× ×××ª ×××©× 6 ××××©×× (×©×ª××××¨ ××¢× ××× ×× ×××× ×××× - ××ª×§××××ª ×©× ××¢× ×× ×§××× ×××ª ××¦× ××××¤××× ×¢× EDSS â¤ 5.5, ×× ××ª×§××××ª ×©× ××¦× × ×§××× ××¦× ××××¤××× ×¢× EDSS â¥ 6). ×. ××ª×××ª ××××¤×× ××ª×¨××¤× ×ª××¢×©× ××¤× ××¨×©× ×©× × ×××¨× ××××× ×××× ×©×¢××¨ ××©×ª××××ª ×¢×××ª××, ×× × ×××¨×××× ××××× ×©×¢××¨ ××©×ª××××ª ×¢×××ª×× ×××¨×©×ª × ×¤××¦×, ×× ×¨××¤× ××××× ×× ×××¨×××××× ××¢××× ×××¨×¤××ª ××¨×©×ª × ×¤××¦× ×× ××¨×¤×× × ×××¨×××××× ××××××ª ×××¢××××ª.	17/03/2024	× ×××¨××××××	××¨×©×ª × ×¤××¦×, Multiple sclerosis

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1. ×××× ××ª×¨×¤×× ×××××× ×¢× ×××× × ××××××ª ×©× ××¨×©×ª × ×¤××¦× (×¢× ×¤× ××§×¨×××¨××× ×× ××¢××× ××× ×¢× ×©× McDonald) ×¢× ×××× ×¤×¢××× ×××× ×××× ×¤×¨×××¨×¡××××ª ×©× ××× ××ª ×¤×¢××× (active SPMS) ×× (Clinically Isolated Syndrome (CIS, ×××ª×× ××ª× ×× ××¨××©××.
  ××××¤×× ×× ××× ×ª× ×××××× ×¢× ×××× ×¤×¨×××¨×¡××××ª ×¨××©×× ××ª (PPMS) ×©××× × ××××¤××× ××ª×¨××¤××ª ×××¢×××××ª ×××¨×©×ª × ×¤××¦×
2. ×××× ××ª×¨×¤××, ×××××× ×¢× ×××× × ××××××ª ×©× ××¨×©×ª × ×¤××¦× ××××× ×¤×¨×××¨×¡××× ×©× ××× × (SPMS) ×¢× ×××¡×××¨×× ×©× RRMS, ×©×× ×¢× EDSS ××¢×¨× 7.5 ×××× ××¢×××ª ××××× ×¤×¢××× (××¢× ××× ×× ×××× ×¤×¢××× ×ª××××¨ ×××× ×××× - ××××¨× ××©× × ××××¨×× ×, ×¤×¢××××ª ×××©× ××××××¨×ª ××¤× × ××¢×× ×××©××, ××¨××× ×©× × ××¢×× ×§××××× ×× × ××¢×× ×§××××× ××××¨× × ×××× ××©× × ××××¨×× × ×××××××ª MRI), ×××××¨× ×§××× ××ª ××ª××¢××ª ×× ××ª×§××××ª ×¨×¦××¤× ×× ×××ª ×××©× 6 ××××©×× (×©×ª××××¨ ××¢× ××× ×× ×××× ×××× - ××ª×§××××ª ×©× ××¢× ×× ×§××× ×××ª ××¦× ××××¤××× ×¢× 5.5 > EDSS, ×× ××ª×§××××ª ×©× ××¦× × ×§××× ××¦× ××××¤××× ×¢× EDSS > 6)
××ª×××ª ××××¤×× ××ª×¨××¤× ×ª××¢×©× ××¤× ××¨×©× ×©× × ×××¨× ××××× ×××× ×©×¢××¨ ××©×ª××××ª ×¢×××ª××, ×× × ×××¨×××× ××××× ×©×¢××¨ ××©×ª××××ª ×¢×××ª×× ×××¨×©×ª × ×¤××¦×, ×× ×¨××¤× ××××× ×× ×××¨×××××× ××¢××× ×××¨×¤××ª ××¨×©×ª × ×¤××¦× ×× ××¨×¤×× × ×××¨×××××× ××××××ª ×××¢××××ª.

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