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L04AC Interleukin inhibitors
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* Pque Poriasis STELARA is indicated for the treatment of moderate to severe plaque psoriasis in adult patients (18 years or older) who have failed to, or have contraindication to or who are intolerant to other systemic therapies including ciclosporin, methotrexate or psoralen plus U.V (PUVA).* Psoriatic ArthritisStelara, alone or in combination with MTX, is indicated for the treatment of active psoriatic arthritis in adult patients when the response to previous non-biological disease-modifying anti-rheumatic drug (DMARD) therapy has been inadequatePediatric plaque psoriasis:STELARA is indicated for the treatment of moderate to severe plaque psoriasis in adolescent patients from the age of 12 years and older, who are inadequately controlled by, or are intolerant to, other systemic therapies or phototherapies.* Crohnâs Disease:STELARA is indicated for the treatment of adult patients with moderately to severely active Crohnâs disease who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a TNF? antagonist or have medical contraindications to such therapies.
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- 23/01/2011
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×ת×××× ×ס×
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ת×ר×× ××××× |
ת××× ×§××× × |
Class Effect |
××¦× ×××× |
×ס×ס ×××××ת
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| ××פ×× ××××ת קר××× ××ר×ת ××××¨× ××× ×× ×ת ×¢× ×§×©× ××××× ×©×××¦× ××פ×× ×§××× ×תר××¤× ××ת ×פ××ת ××שפ×ת ×-anti TNF ×× Vedolizumab. |
12/01/2017 |
×ס×ר××× ×ר×××××× |
|
Crohn's disease |
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| ××קת ×פרק×× ×¤×¡×ר××××ת פע××× ××תק××ת ××שר ×ת×××× ×ת×ש×ר×× ××שפ×ת ×-DMARDs ××× × × ×ספקת |
21/01/2016 |
ר×××××××××× |
TOFACITINIB, ADALIMUMAB, USTEKINUMAB, SECUKINUMAB, ABATACEPT, ETANERCEPT, INFLIXIMAB |
Psoriatic arthritis |
|
פס×ר××××ס ××תק××× ×× ×××:
- ×. ××××× ×¡××× ×××× ××××:
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- 2. × ××¢×× ×××××¨× ×××£ ר××ש×× - ×××ר×× ××× ××××× ×¤× ××, צ×××ר, ×§×פ××× ×¢×ר, ×פ×ת ×××××, ×פ×ת ר×××××, ×××ר ××× ××××× ×××ש××.
- ×. ××××× ×§××× ×©× × ××פ×××× ×¡×ס××××× ×פ××ת ××× ×©×פ×ר ×©× 50% ×פ××ת ×-PASI ×××ר ס××× ×××פ×× ××ש×××× ×ת×××ת ×××פ××. ××ת×××ס ××××× ××¢×× × ×¢× ×¤×¡×§× (1)(×)(2) ××××× ×§××× ×©× × ××פ×××× ×¡×ס××××× ×פ××ת ××× ×©×פ×ר ×ש××¢××ª× ×××ר ס××× ×××פ×× ××ש×××× ×ת×××ת ×××פ××;
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23/01/2011 |
×¢×ר ×××× |
ADALIMUMAB, IXEKIZUMAB, CERTOLIZUMAB PEGOL, USTEKINUMAB, SECUKINUMAB, GUSELKUMAB, ETANERCEPT, INFLIXIMAB, TILDRAKIZUMAB |
Psoriasis |
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- ×. ×××× ×פ×ש×ת ××¢× ×-50% ×©× ×©×× ×××£ ×× PASI ××¢× 50;
- ×. × ××¢×× ×××××¨× ×××£ ר××ש×× - ×××ר×× ××× ××××× ×¤× ××, צ×××ר, ×§×פ××× ×¢×ר, ×פ×ת ×××××, ×פ×ת ר×××××, ×××ר ××× ××××× ×××ש××;
- 2. ××××× ×§××× ×©× × ××פ×××× ×¡×ס××××× ×פ××ת ××× ×©×פ×ר ×©× 50% ×פ××ת ×-PASI ×××ר ס××× ×××פ×× ××ש×××× ×ת×××ת ×××פ××; ××ת×××ס ××××× ××¢×× × ×¢× ××××ר ×פסקת ××©× × (×)(2) - ××××× ×§××× ×©× × ××פ×××× ×¡×ס××××× ×פ××ת ××× ×©×פ×ר ×ש××¢××ª× ×××ר ס××× ×××פ×× ××ש×××× ×ת×××ת ×××פ××;
- 3. ×תר××¤× ×ª×× ×ª× ×¢× ×¤× ××¨×©× ×©× ×¨××¤× ××××× ××ר××××××××.
- ×. ××קת ×פרק×× ×¤×¡×ר××××ת פע××× ××תק××ת ××שר ×ת×××× ×ת×ש×ר×× ××שפ×ת ×-DMARDs ××× × × ×ספקת.
- ×. ××פ×× ××××ת קר××× ××ר×ת ××××¨× ××× ×× ×ת ×¢× ×§×©× ××××× ×©×××¦× ××פ×× ×§××× ×תר××¤× ××ת ×פ××ת ××שפ×ת ×-anti TNF ×× Vedolizumab.
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CILAG
ס×××¨× - Stelara
true
השינוי האחרון נעשה בֹ־7 באוקטובר 2014 ב־07:47