קסאלקורי 250 מ"ג - Xalkori 250 mg

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×§×¡×××§××¨× 200 ×"× - Xalkori 200 mg

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L01ED
Anaplastic lymphoma kinase (ALK) inhibitors

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Crizotinib 250MG âL01ED01

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×¤××× - PER OS

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×§×¤×¡××××ª, CAPSULES
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XALKORI is indicated for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) that is anaplastic lymphoma kinase (ALK)-positive. Xalkori is indicated for the treatment of patients with metastatic NSCLC whose tumors are ROS1-positive.

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10/01/2012

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××ª××××	×ª××¨×× ×××××	×ª××× ×§××× ×	Class Effect	××¦× ××××	××¡××¡ ××××××ª
×××¤×× ×××× ××§×¨×¦×× ××× ××ª×§×××ª ×©× ××¨××× ××¡×× non small cell(NSCLC) ×¢× ××××¦×× ×©×××××ª ×-EGFR ×©×× ××¢×× ××××¦×× ××××××ª ×-ALK ( Anaplastic Lymphoma Kinase positive))	10/01/2012	××× ×§××××××		ALK+ NSCLC
ROS1+ NSCLC	12/01/2017	××× ×§××××××		ROS1 positive NSCLC

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×. ××ª×¨××¤× ×ª×× ×ª× ××××¤×× ×××§×¨×× ××××:

1. ××ª×¨××¤× ×ª×× ×ª× ××××¤×× ×××× ××§×¨×¦×× ××× ××ª×§×××ª ×©× ××¨××× ××¡×× non small cell (NSCLC) ×¢× ××××¦×× ×©×××××ª ×-EGFR ×©×× ××¢×× ××××¦×× ××××××ª ×-ALKâ (Anaplastic Lymphoma Kinase positive) ××××× ××××ª× ×××× ××××× ×××× ××××¤×× ××©×××© ×ª×¨××¤××ª ×××× ×××ª×¨××¤××ª ×××¤××¨×××ª ×××× â Alectinib, Brigatinib, Ceritinib, Crizotinib, Lorlatinib.

2. ××ª×¨××¤× ×ª×× ×ª× ××××¤×× ×××× ××§×¨×¦×× ××× ××ª×§×××ª ×©× ××¨××× ××¡×× non small cell (NSCLC) ×¢× ××××¦×× ×©×××××ª ×-EGFR ×©×× ××¢×× ××××¦×× ××××××ª ××¡×× ROS1.

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×¢××× ××¨××¤× 03.01.2020

×¢××× ××¦×¨××	Â ×¢××× ××¦×¨×× ×¢××¨××ª 03.01.2021 ×¢××× ××¦×¨×× ×¢×¨×××ª - ÙØ´Ø±Ø© ÙÙÙØ³ØªÙÙÙ Ø¨Ø§ÙÙØºØ© Ø§ÙØ¹Ø±Ø¨ÙØ© 03.01.2021 ×¢××× ××¦×¨×× ×× ××××ª - Patient information leafletâ 03.01.2021

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×××¤××© ××××¨××	××××¨×× ×-PubMed
××××¢ ××¨×©×ª	RxList WebMD Drugs.com
×©× ××¦×¨×	PFIZER MANUFACTURING DEUTSCHLAND GMBH, GERMANY
×©× ××¢× ××¨××©××	PFIZER PHARMACEUTICALS ISRAEL LTD
×¨××©×××	×ª××¨×× ×××©×: 11/2011. ×¨××©××× ××ª××¨××: 01/2017
×ª××¨×× ×¢×××× ×××¨××	15/05/19

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השינוי האחרון נעשה בֹ־25 ביוני 2025 ב־16:13

קסאלקורי 250 מ"ג - Xalkori 250 mg

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