× ×ª×× × ×ª×¨×פ×
××רש×
| ק×××¦× ×¤×¨×ק×××××ת (ATC4)
|
L01FF
PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
|
| ×ר××× ×¤×¢×× (ATC5)
|
Â
|
| צ×רת ×ת×
|
ת××-×ר××× - I.V
|
| צ×רת ××× ××
|
תר××× ×××× ×ª ת×××¡× ×××× ×¤××××, CONCENTRATE FOR SOLUTION FOR INFUSION
××× ×עת ××× ×× ×תר ×× ×רע×× ×ש ××××× ×ת ×תר××¤× ××ת×× ×××× ×× ××××××¥ ××¤× ×©××פ××¢ ××¢××× ×צר××
|
| ×ת××××
|
Jemperli is indicated as monotherapy for the treatment of adult patients with mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) recurrent or advanced endometrial cancer (EC) that has progressed on or following prior treatment with a platinum-containing regimen.
|
| × ×ª×× × ×ס×
|
ת×ר×× ××××× ×ס×
- 03/02/2022
|
×××××ת ×ס×
- תר××¤× ×××××ת ×ר×ש×× ×¢'× ×¨××¤× ××××× ×× ××××× ××רת
|
×ת×××× ×ס×
| ×ת×××× |
ת×ר×× ××××× |
ת××× ×§××× × |
Class Effect |
××¦× ×××× |
×ס×ס ×××××ת
|
| ×. ×תר××¤× ×ª×× ×ª× ×××× ×תרפ×× ×××פ×× ×סר×× ×¨×× ×ר××¨×ª× ××××× ×©××× MSI-H microsatellite instability high)) ×× dMMR (mismatch repair deficient) ש××××ª× ×תק××× ×××ר ×§× ××פ×× ××× ×× ××תר. ×. ××××× ××××ª× ×ª××× ××××× ××××ת ×תר××¤× ××ת ×××× ×תר×פ×ת ××שת××××ת ××שפ×ת ×-Checkpoint inhibitors.
|
03/02/2022 |
××× ×§×××××× |
|
סר×× ×¨××, Endometrial cancer |
|
| ×. ×ש×××× ×¢× ××××תרפ×× ××××ר ××× ×××× ×תרפ××, ×××פ×× ×§× ×¨×ש×× ×סר×× ×©× ×¨×ר×ת ×ר×× ×ש×× ×תק×× ×¨×ש×× × ×× × ×ª×× ×× ×××ר, ××× ××קר×× ×©× ×©×ר×ת ×××× ×××ר × ×ת××, ××××× ×©××× MSI-H (microsatellite instability high) ×× dMMR (mismatch repair deficient). ××©× ×××פ×× ×ת×ש×ר ××ת×××× ×× ×× ××¢×× ×¢× ×©××ש ×©× ××. ×. ××××× ××××ª× ×ª××× ××××× ××××ת ×תר××¤× ××ת ×××× ×תר×פ×ת ××שת××××ת ××שפ×ת ×-Checkpoint inhibitors. ×. ××ª× ×תר××¤× ×××××¨× ×××¢×©× ××¤× ××¨×©× ×©× ××××× ×××× ×§××××××.
|
19/02/2025 |
××× ×§×××××× |
|
סר×× ×¨×ר×ת ר××, Endometrial cancer |
|
|
ש×××ש ×ס×
-
|
×ס×רת ××××× ×ס×
- ×תר××¤× ×ª×× ×ª× ×××פ×× ××קר×× ××××:
- ×ש×××× ×¢× ××××תרפ×× ××××ר ××× ×××× ×תרפ××, ×××פ×× ×§× ×¨×ש×× ×סר×× ×©× ×¨×ר×ת ×ר×× ×ש×× ×תק×× ×¨×ש×× × ×× × ×ª×× ×× ×××ר, ××× ××קר×× ×©× ×©×ר×ת ×××× ×××ר × ×ת××, ××××× ×©××× (MSI-H (microsatellite instability high ×× dMMR (deficient mismatch repair).
××©× ×××פ×× ×ת×ש×ר ××ת×××× ×× ×× ××¢×× ×¢× ×©××ש ×©× ××
- ×××× ×תרפ×× ×××פ×× ×סר×× ×¨×ר×ת ר×× ×ר××¨×ª× ××××× ×©××× (MSI-H (microsatellite instability high ×× dMMR (deficient mismatch repair) ש××××ª× ×תק××× ×××ר ×§× ××פ×× ××× ×× ××תר
- ××××× ××××ª× ×ª××× ××××× ××××ת ×תר××¤× ××ת ×××× ×תר×פ×ת ××שת××××ת ××שפ×ת ×Â-Checkpoint inhibitors
- ××ª× ×תר××¤× ×××××¨× ×××¢×©× ××¤× ××¨×©× ×©× ××××× ×××× ×§××××××
|
|
| ×¢××× ×ר××¤× ××××ר×ת ××¢×××
|
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| ××פ×ש ×××ר××
|
×××ר×× ×-PubMed
|
| ××××¢ ×רשת
|
RxList WebMD Drugs.com
|
| ×©× ×צר×
|
GLAXO SMITHKLINE TRADING SERVICES LIMITED, IRELAND
|
| ×©× ××¢× ×ר×ש××
|
GLAXO SMITH KLINE (ISRAEL) LTD
|
| ר×ש×××
|
ת×ר×× ××ש×: 4/2021. ר×ש××× ×ת×ר××:
|
| ת×ר×× ×¢×××× ××ר××
|
09/02/24
|
ת×ר×× ×¢××××: 09/02/24
GLAXO
×'×פר×× - Jemperli
true
השינוי האחרון נעשה בֹ־17 ביוני 2025 ב־12:13
